Mouse brain slices brought back to life after being frozen for a week (www.newscientist.com)
from TacoButtPlug@sh.itjust.works to science@mander.xyz on 20 Feb 21:12
https://sh.itjust.works/post/33156458

archive.ph/VQauU

#science

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Valmond@lemmy.world on 20 Feb 21:24 next collapse

This is incredible.

Maybe anti-cryo people can finally shut it :-)

On a more serious note, this paves the way for cryopreserving organs and of course later on, our brain, mind & consciousnesses for a future thawing.

Edit: anti-cryo downvotes incoming!

Semi_Hemi_Demigod@lemmy.world on 20 Feb 21:54 collapse

Cryo works for animals and tissues up to a certain size. The problem is that once it’s a bit bigger than a guinea pig it gets a lot harder to reheat evenly which causes damage. Imagine if your skin and muscles were thawed but not your heart, for example.

Valmond@lemmy.world on 20 Feb 22:24 collapse

The size of things we can cryopreserve and thaw is growing bigger every year, hence the importance of the article.

Soon we will be able to cryopreserve a human kidney, then a liver and so on.

Semi_Hemi_Demigod@lemmy.world on 20 Feb 22:28 collapse

I fully expect individual organs to be cryo preserved which is fantastic. Even a portion of a liver would be significant.

But I think the laws of thermodynamics will prevent preservation of whole heads, let alone bodies. (And then there’s all the other issues with cryo like what happens when the clinic goes out of business.)

Valmond@lemmy.world on 20 Feb 22:54 collapse

There is nothing preventing a rapid cooling the problem is to get water removed/replaced because it creates ice crystals. We can already do this somehow.

The problem with thawing is how do you heat it uniformly.

I have never heard about the laws of thermodynamics would hinder this, any information gladly accepted.

And as for the business, well it’s better than dying, at least there is a chance!

Semi_Hemi_Demigod@lemmy.world on 20 Feb 23:06 collapse

It’s related to thermodynamics but it’s basically the square-cube law: the bigger you get the more your internal volume grows compared to your size.

Heating something large evenly is very difficult because of this. It’s why burritos are lava on the outside and icicles on the inside out of the microwave, or why you need to cook a large roast slowly.

Valmond@lemmy.world on 20 Feb 23:15 collapse

Hopefully we won’t use basic microwaves then :-)

I read about nano particles spread out in the tissues, made to vibrate (probably by EM) to heat up larger portions uniformly.

It’s just a matter of time and effort.

Semi_Hemi_Demigod@lemmy.world on 20 Feb 23:16 collapse

Nanoparticles might do the trick!

Bob_Robertson_IX@discuss.tchncs.de on 21 Feb 01:14 next collapse

Everyone is all impressed with the cryo part, and I’m more shocked that a sliced up brain can still function.

Kolanaki@pawb.social on 21 Feb 01:19 collapse

You should check out the studies on split brains in humans, where they had to basically separate the left and right hemispheres for medical reasons and the weird shit that the patient ends up experiencing. Or even how they have been able to make machines that run off bits of rat brain or just collections of lab grown neurons instead of computer chips.

indomara@lemmy.world on 22 Feb 12:26 collapse

Yeah, this stuff is wild, there was a little girl years ago who had a seizure disorder, and they removed one half of her brain, she somehow kept most functions and could walk but had some weakness in the limbs on the opposing side.

I just looked her up - holy shit look at how she is today!

npr.org/…/neuroplasticity-plasticity-glass-half-f…

Rozz@lemmy.sdf.org on 21 Feb 03:14 next collapse

What a novel sentence

fraksken@infosec.pub on 22 Feb 08:12 collapse

I wonder what it was thinking.

Redderthanmisty@lemmygrad.ml on 23 Feb 04:48 collapse

“That was cool”