Several Psychiatric Disorders Share The Same Root Cause, Study Reveals (www.sciencealert.com)
from cm0002@lemmy.world to science@mander.xyz on 09 Feb 2025 16:27
https://lemmy.world/post/25356797

#science

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Bort@hilariouschaos.com on 09 Feb 2025 17:12 next collapse

TLDR: So this is saying there are some genetic variants that cause cascading protein malformations in developing brains, which leads to a higher risk of developing certain psychiatric disorders, including autism, ADHD, schizophrenia, bipolar disorder, major depressive disorder, Tourette syndrome, obsessive-compulsive disorder, and anorexia.

kryptonidas@lemmings.world on 09 Feb 2025 21:51 collapse

It doesn’t sound super surprising that different malformations in the brain even though caused by the same underlying condition can result in very varied effects on behavior.

Good stuff though. (The research)

Neuromancer49@midwest.social on 09 Feb 2025 17:15 next collapse

And that root cause? The BRAIN.

All jokes aside, this sort of research forms the backbone of modern medicine. It’s also at risk with the Trump administration targeting federal research grants from the NIH.

For those of us in the US, call and email your representatives, join protests, and get organized.

AbouBenAdhem@lemmy.world on 09 Feb 2025 18:30 next collapse

I don’t know if a pleiotropic relationship between 109 different genes can be called “the same root cause”. Maybe “a large complex of interacting causes”?

admin@lemmy-mormonsatan-u23030.vm.elestio.app on 09 Feb 2025 23:24 collapse

Fair point!

DavidGarcia@feddit.nl on 09 Feb 2025 20:22 next collapse

scientists need to get their act together. chop chop, fix my stupid brain already

some_guy@lemmy.sdf.org on 09 Feb 2025 21:19 next collapse

Here’s the list: autism, ADHD, schizophrenia, bipolar disorder, major depressive disorder, Tourette syndrome, obsessive-compulsive disorder, and anorexia.

admin@lemmy-mormonsatan-u23030.vm.elestio.app on 09 Feb 2025 23:24 next collapse

Interesting article. Thanks for this post!

Monument@lemmy.sdf.org on 10 Feb 2025 16:57 collapse

This feeds so much into my confirmation bias and I’m captivated by it.

Like how it’s a trope at this point that people with ADHD also demonstrate some behaviors associated with autism.

I want to see the Venn diagram of people with these diseases overlaid onto the Venn diagram of their genetic tests for the identified mutations.

Do certain mutations cluster to certain diseases?!