Vaccine breakthrough means no more chasing strains (news.ucr.edu)
from ZeroCool@slrpnk.net to science@mander.xyz on 18 Apr 2024 01:59
https://slrpnk.net/post/8730232

#science

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vk6flab@lemmy.radio on 18 Apr 2024 02:12 next collapse

Extraordinary claims require extraordinary proof.

As it is, the first time this was posted, biologists and pharmacists discussed the merits of the claims and came to the conclusion that this was unlikely to be real.

Specifically the approach would probably be thwarted the second time you attempted to use this method because your immune system would attack the vaccine.

The discussion also pointed out that this was why the second dose of Astrazeneca during the COVID pandemic was less effective.

Disclaimer: I’m not a medical professional and don’t pretend to be one online. I’m reciting from memory. YMMV.

ZeroCool@slrpnk.net on 18 Apr 2024 02:32 collapse

Extraordinary claims require extraordinary proof.

As it is, the first time this was posted, biologists and pharmacists discussed the merits of the claims and came to the conclusion that this was unlikely to be real.

Link please? Kinda feel like I shouldn’t have had to ask for that based on how you chose to begin your comment but here we are.

vk6flab@lemmy.radio on 18 Apr 2024 03:55 collapse

hexbear.net/post/2315391

obelix@lemmy.world on 18 Apr 2024 12:31 next collapse

Lol.

bjorney@lemmy.ca on 18 Apr 2024 13:20 collapse

So the “biologists and pharmacologists” you are citing are just armchair scientists in the Lemmy comment section

MotoAsh@lemmy.world on 18 Apr 2024 13:51 next collapse

On Hexbear, no less.

Umbrias@beehaw.org on 18 Apr 2024 22:17 collapse

Unaccountable armchair ‘scientists’ on hexbear no less. Lol.

Also once you finally get to someone discussing the content of the paper the entire tone about plausibility changes.

GrymEdm@lemmy.world on 18 Apr 2024 02:12 next collapse

Super interesting! I’m going to file this under “hope it’s true, will wait for testing/confirmation because the claims are amazing”.

1984@lemmy.today on 18 Apr 2024 04:52 next collapse

I don’t vaccinate, and that is enough to get downvoted. :)

zoomshoes@lemmy.zip on 18 Apr 2024 05:08 next collapse

Congratulations.

DragonTypeWyvern@literature.cafe on 18 Apr 2024 05:32 collapse

Too bad that dumbass was vaccinated as an infant

spartanatreyu@programming.dev on 18 Apr 2024 06:59 next collapse

Luckily for you, there’s not a vaccine for stupidity.

MotoAsh@lemmy.world on 18 Apr 2024 13:52 collapse

Yes there is, it’s just also made of toxic chemicals and increasing in price lately.

Diplomjodler3@lemmy.world on 18 Apr 2024 07:22 next collapse

So what do you know that literally all the scientists in the world don’t?

suodrazah@aussie.zone on 18 Apr 2024 12:49 next collapse

Don’t procreate.

Donkter@lemmy.world on 18 Apr 2024 14:25 next collapse

You’re getting down voted because your post doesn’t meaningfully contribute.

PlantDadManGuy@lemmy.world on 18 Apr 2024 15:25 collapse

Obvious troll is obvious.

itsnicodegallo@lemm.ee on 18 Apr 2024 07:21 next collapse

Note that some studies show nine mouse days are roughly equivalent to one human year.

Excuse me?

jol@discuss.tchncs.de on 18 Apr 2024 11:59 next collapse

Basically mice procrastinate much less than people.

runner_g@lemmy.blahaj.zone on 18 Apr 2024 12:56 next collapse

Given the position of this statement in the article, I’m guessing they are trying to imply a correlation in rate of aging. Like 1 dog year = 7 human years. They are further implying that if a mouse maintains immunity for 90 days, a human would maintain immunity for 10 years.

It should be clear that it is the reporter stating this, not the original authors of the study.

Pyr_Pressure@lemmy.ca on 18 Apr 2024 14:05 collapse

I’m no cell biologist but I don’t think immunity works that way. I don’t know enough to dispute it though.

runner_g@lemmy.blahaj.zone on 18 Apr 2024 14:18 next collapse

I am a molecular biologist, and it kinda works this way. B cells are called memory cells because they hold onto that “memory” of the invader for a really long time. You probably haven’t had an MMR or a Tetanus vaccine in 10+ years because the body is really good at remembering. But we have to get flu boosters every year because the flu mutates so rapidly that traditional b cells won’t recognize the flu after a year of mutating. (RNA viruses can’t correct their mutations so they change much faster than bacteria or DNA viruses). RNAi was still pretty new when I was in school and I haven’t kept up with the research so I can’t speak to it’s effectiveness at long term immunity.

Pyr_Pressure@lemmy.ca on 18 Apr 2024 14:27 collapse

I know enough about that, the part I was skeptical about though was the assumption that if a mouse is immune for 90 days, a human would be immune for 10 years.

runner_g@lemmy.blahaj.zone on 18 Apr 2024 15:52 collapse

And you are absolutely right to be skeptical about that, that is a crazy level of extrapolation.

kemsat@lemmy.world on 18 Apr 2024 14:31 next collapse

I assumed it had to do with heartbeats. Mice hearts beat much faster than human hearts, and I think of the heartbeat like a computer’s clock or an engine’s RPM. If you increase that, the rate of everything else increases.

Anticorp@lemmy.world on 18 Apr 2024 16:32 collapse

It is good that you recognize that you don’t know enough to dispute it. Now just recognize that people who do know enough aren’t disputing it.

Daxtron2@startrek.website on 18 Apr 2024 13:37 collapse

You’re excused

prole@sh.itjust.works on 18 Apr 2024 13:11 next collapse

I thought the thumbnail was a Smurf hand holding a crackpipe… I think I need to get more sleep.

Anticorp@lemmy.world on 18 Apr 2024 16:30 collapse

Or possibly less crack.

Reddfugee42@lemmy.world on 18 Apr 2024 15:35 collapse

So I can stop drinking bleach?

Anticorp@lemmy.world on 18 Apr 2024 16:30 collapse

No more light bulbs up the arse either.

clay_pidgin@sh.itjust.works on 18 Apr 2024 17:06 collapse

Aww man, there go my weekend plans.

Anticorp@lemmy.world on 18 Apr 2024 17:39 collapse

Well, you can still do it if you enjoy it.