AI-powered CRISPR could lead to faster gene therapies, Stanford Medicine study finds (med.stanford.edu)
from DarkBluemetal@lemmy.world to technology@lemmy.world on 09 Oct 19:40
https://lemmy.world/post/37124366

#technology

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Horta@discuss.tchncs.de on 09 Oct 20:19 next collapse

“Hey…Crisper.GP…T…think…you’ve mixed up the genes for my ass and…elbows…”

“Oh, you’re totally alright! I apologise about that. 😀”

TribblesBestFriend@startrek.website on 09 Oct 20:51 next collapse

“Oh, you’re totally alright! I apologise about that. 😀”

Here your ass on your elbow like you asked

[deleted] on 10 Oct 04:41 next collapse

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echodot@feddit.uk on 10 Oct 08:11 collapse

To be honest you’re probably better off just making a T-Rex from the start let it eat you and just get it over with.

webghost0101@sopuli.xyz on 09 Oct 20:53 next collapse

Machine learning sure, but an llm? For anything other then as a module to translate abstract data into words that just seem weird

echodot@feddit.uk on 10 Oct 08:17 collapse

Well I’m sure you know more than the scientists at Stanford university.

webghost0101@sopuli.xyz on 10 Oct 15:28 collapse

I am not saying i understand it at all. My comment is genuine, not rhetorical.

On the contrary i express that i do not understand this to the point of deeming it strange or weird, triggering my curiosity.

I was hoping someone would chime in an explain how text generator techniques (which i do know alot about) known to have no capacity to use real world reason or logic can be used to help solve dna puzzles unless as a sub module of general machine learning. In which that later case would be within my understanding

panda_abyss@lemmy.ca on 09 Oct 21:22 next collapse

I am asking that all the people doing this watch Jurassic Park at least once.

I’ll let experts do their thing, but this kind of thing worries me. I never had “there is no singularity, AI just engineers a generic disease by accident and kills is all” on my bingo.

Telorand@reddthat.com on 09 Oct 23:53 next collapse

This is actually an excellent use case for AI. Physics and chemistry as scientific disciplines are lots of complex pattern recognition and manipulation. AI is just a pattern recognition and generation engine, despite what the tech bros and apologists like to tell us.

What these engines generate will ultimately be vetted by experts before it even goes to trials. Scientists don’t just take things on blind faith simply because a robot or even another expert comes up with something; their entire deal is to understand their particular field of study in great detail, after all!

Cybersteel@lemmy.world on 10 Oct 00:59 collapse

Back in the day, I used to fold proteins at home.

Telorand@reddthat.com on 10 Oct 06:02 next collapse

Same

echodot@feddit.uk on 10 Oct 08:15 collapse

There’s something similar that you can do with categorising stars. Basically they want to map as much of the universe as we can see. We’ve got the photos the problem is is that when you zoom in on a 1 mm by 1 mm patch of sky 1,100,000 new stars appear. It’s going to take a while, even with AI.

You never know you might find a Dyson sphere one day.

Reverendender@sh.itjust.works on 10 Oct 00:57 next collapse

Eh. Read the book first.

echodot@feddit.uk on 10 Oct 08:12 collapse

Of course the actual moral of Jurassic Park is have a well staffed IT team and not just one random guy who you under pay.

9488fcea02a9@sh.itjust.works on 10 Oct 01:57 next collapse

Lol… people downvoting stanford university

Lemmy is a wild place… left wing maga, i guess

Perspectivist@feddit.uk on 10 Oct 04:39 next collapse

It says AI in the title. That’s all information they need. Most people on social media don’t think - they react.

echodot@feddit.uk on 10 Oct 08:09 collapse

No I doesn’t.

The problem is the term AI has become so broadly used that it’s become meaningless. There is a popular quote about how the quota doesn’t want AI to replace artistic jobs, as if it will. As if generative AI and large language models and projects like this are the same.

When the bubble bursts, (please let it be soon) we’re still going to have all of the science AIs because those are actually useful. What we don’t need is AI girlfriends.

Perspectivist@feddit.uk on 10 Oct 08:13 collapse

AI-powered

Yes it does.

echodot@feddit.uk on 10 Oct 08:34 collapse

Yes I know the title has the word AI powered in it. I never claimed otherwise.

ExcessShiv@lemmy.dbzer0.com on 10 Oct 09:38 next collapse

No it doesn’t

Yes you did

echodot@feddit.uk on 10 Oct 11:26 collapse

If you’re going to quote some text quote the actual text because you’ll notice that you’re changing it.

I didn’t say “no it doesn’t” I said “no I doesn’t” which is a different sentence.

ExcessShiv@lemmy.dbzer0.com on 10 Oct 11:40 next collapse

Yeees, your obvious typo is totally invalidating my previous statement…

echodot@feddit.uk on 10 Oct 16:04 collapse

It wasn’t a typo it’s a quote from Futurama. Fry says it when the professor says he’s dumb.

Grimy@lemmy.world on 10 Oct 14:36 collapse

Now that is some bullshit if I’ve ever seen it. Take the loss bro.

echodot@feddit.uk on 10 Oct 16:02 collapse

Just read the actual quote it doesn’t say what he says it says and you’ll notice that no point have I ever edited it.

They misquoted me because they didn’t read the quote properly and then doubled down on it. Meanwhile you are now arguing about it despite the fact that it is demonstrably evident that you are wrong

Grimy@lemmy.world on 10 Oct 16:14 collapse

The Futurama quote is “No I’m doesn’t” and doesn’t make any sense in this context even if it was properly transcribed.

Bro, either you are being insanely unclear, in which case it’s still on you, or you are lying to save face.

There is not one person that thought you meant some obscure Futurama quote spealt “No I’m doesn’t” instead of the obvious “No it doesn’t”. We don’t live in your head, you are communicating terribly and trying to spin it on everybody else. I mean, thinking most people even know Futurama enough to spot the quote even if it was properly written is a HUGE ask.

I’m not trying to be overly harsh here but this is a bit ridiculous, sorry.

Perspectivist@feddit.uk on 10 Oct 09:41 collapse

I make three claims and your response only fits one of them.

It says AI in the title.

No it doesn’t.

That’s all information they need.

No it doesn’t.

Most people on social media don’t think - they react.

No it doesn’t.

[deleted] on 10 Oct 11:27 collapse

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rapchee@lemmy.world on 10 Oct 05:19 collapse

it’s useless hype, “ai could do x one day” is speculation at best

Perspectivist@feddit.uk on 10 Oct 16:09 collapse

DeepMind’s AlphaFold solved the decades-old protein folding problem, and its results are already being used in drug and vaccine development.

rapchee@lemmy.world on 11 Oct 07:02 collapse

is this what the article talks about?

Perspectivist@feddit.uk on 11 Oct 07:29 collapse

CRISPR is the tool that lets us precisely edit genes in DNA, which contain the instructions for making proteins. AlphaFold is the AI tool that helped us understand what those edits actually do. It’s the 3D shape of the protein that determines its function - without understanding protein folding, gene editing would be like changing code in a language you don’t fully understand and just hoping it works.

rapchee@lemmy.world on 12 Oct 21:09 collapse

so while not the same, it’s a fairly similar field, it is a safe to assume that similar tools can be used. not yet though, the tool is not ready.
why is there a study for this? other than hype - for “ai”, which this arguably isn’t

Perspectivist@feddit.uk on 13 Oct 03:39 collapse

“ai could do x one day” is speculation at best

AI can do, and has done X already. That’s my point.

Muffi@programming.dev on 10 Oct 08:08 next collapse

What a shame that we have created a world where this will only benefit a wealthy minority.

Treczoks@lemmy.world on 10 Oct 19:46 next collapse

… or to funny looking specimen. Radioactivity no longer required.

muusemuuse@sh.itjust.works on 10 Oct 21:45 collapse

This seems irresponsible.

There was an old game from the PlayStation days called Xenogears. There was a population of mutants and monsters in it than came about from fucking with DNA irresponsibly. I’m reminded of that obnoxious rat-man from the Kislev prison.