First live birth of a chimeric monkey using embryonic stem cell lines (www.cell.com)
from i_have_no_enemies@lemmy.world to technology@lemmy.world on 09 Nov 2023 23:58
https://lemmy.world/post/8039790

#technology

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i_have_no_enemies@lemmy.world on 10 Nov 2023 00:02 next collapse

<img alt="" src="https://lemmy.world/pictrs/image/3e6f34d6-b73c-45da-8029-8cf82370a6af.jpeg">

BustlingChungus@lemmy.world on 10 Nov 2023 00:17 next collapse

Planet of the Apes, here we come!

ElectroNeutrino@lemmy.world on 10 Nov 2023 00:56 next collapse

Ed… Ward…

pastermil@sh.itjust.works on 10 Nov 2023 11:17 collapse

not that chimera!

subspaceinterferents@lemmy.world on 10 Nov 2023 01:17 next collapse

An a.i. clarification of the article’s summary: Researchers proved that stem cells from mammals can turn into any cell type like cells from an early embryo. These are called naive stem cells. They’ve shown naive stem cells work great in rodents, but not as well in primates since the donor cells don’t match the host embryo. So they tried different conditions to produce naive stem cells from monkeys and got better at growing chimeric embryos. A chimeric monkey is one that has cells from two different embryos combined together. They created an aborted fetus and live chimeric monkey with high donor cell numbers. Testing showed the donor cells integrated into many tissues (including sex organs and placenta) of the chimeric monkeys, up to 90%. This is a big deal for researching naive stem cells and genetically modifying primates.

rhythmisaprancer@kbin.social on 10 Nov 2023 04:30 collapse

I wouldn't be able to tell you how accurate this synopsis is, but I am curious what reasons we have to be genetically modifying primates...

subspaceinterferents@lemmy.world on 10 Nov 2023 14:33 next collapse

I can only imagine that at some point in the future humans will be on deck for such modifications. Brave New World, eh?

rhythmisaprancer@kbin.social on 10 Nov 2023 16:44 collapse

☠️☠️ I was thinking more like as a replacement for that genetically modified pig that they used a (heart?) from recently but ya, I can only imagine you are right.

metallic_z3r0@infosec.pub on 10 Nov 2023 17:55 collapse

I mean, that seems like the best solution to rejection: cloning the patient’s germ line and chimerically colonizing the replacement.

RazorsLedge@lemmy.world on 11 Nov 2023 02:01 next collapse

It’s not hard to imagine. Maybe remove or correct some undesirable genes, for example those associated with diseases. Or perhaps reduce genes associated with violence or aggression. There are a lot of reasons.

webghost0101@sopuli.xyz on 13 Nov 2023 01:29 collapse

To learn and understand how biology works.

Imagine no longer needing organ donors because we can grow anyone with these cells or regeneratin a finger or nose after a freak accident. Before we get there we need to fully understand and test first.

And yeah u guess human modifying is something people will eventually do as well i guess.

TheLordHumungus@lemmy.world on 10 Nov 2023 06:12 next collapse

“Yeah, but your scientists were so preoccupied with whether or not they could, they didn’t stop to think if they should.” Dr. Ian Malcolm

FlyingSquid@lemmy.world on 10 Nov 2023 12:28 collapse

Will it throw chimeric poo?