Cancers can be detected in bloodstream three years prior to diagnosis (hub.jhu.edu)
from Gsus4@mander.xyz to technology@lemmy.world on 14 Jun 02:22
https://mander.xyz/post/32030688

#technology

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pelespirit@sh.itjust.works on 14 Jun 02:53 next collapse

I thought cancer comes a goes all the time, wouldn’t that give a lot of people false positives and a start to the cascade of healthcare?

catloaf@lemm.ee on 14 Jun 03:24 next collapse

Not really, no. It’s only really cancer once the cells multiply uncontrollably. Yes, sometimes cells don’t properly perform apoptosis, but there are other mechanisms that will target and kill those precancerous cells. Only once those other mechanisms fail does it become true cancer.

Besides, even if this test did come back positive, they’d still have to identify a tumor and monitor. If you have a teeny-tiny benign tumor that isn’t hurting anything, the best course of action is to just leave it alone and monitor. Any surgical procedure risks spillage, which is basically human-induced metastasis.

pelespirit@sh.itjust.works on 14 Jun 03:28 collapse

That makes sense if I’m understanding you correctly. You might have cancerous cells, but it’s not actually cancer.

catloaf@lemm.ee on 14 Jun 03:45 collapse

Right. Like you might walk by someone with a cold, and inhale a small number of their virus particles. But your immune system can handle that. If you spend a lot of time with them face-to-face, the virus gets a foothold (because of inhaling more viruses, this part isn’t a perfect metaphor) and starts multiplying, it can overwhelm the first line of defense and become an infection.

eletes@sh.itjust.works on 14 Jun 05:57 collapse

The article says they’re detecting DNA shedding of genetic mutations. I think one example of this could be cancer caused by HPV should shed DNA that they could identify.

It’s probably different but that’s what I’m thinking from that line

Bo7a@lemmy.ca on 14 Jun 11:01 collapse

Look up extra-cellular vesicles. This is where the magic is.

BigMacHole@sopuli.xyz on 14 Jun 03:23 next collapse

What? This BETTER not be US funded Research! I DONT want MY Tax Dollars going to THIS when there’s SAD BILLIONAIRES still out there!

-LITERALLY everyone who Voted for Trump!

sqgl@sh.itjust.works on 14 Jun 04:51 next collapse

Why should the world benefit from our taxpayer funded research? I want my taxes spent on training Americans so as to let the world watch (for free) fast running and swimming.

Am still waiting for a skipping event in the Olympics.

LainTrain@lemmy.dbzer0.com on 14 Jun 05:49 collapse

The world isn’t benefitting from your research, you benefit from the world’s research based off your own research, on and on it goes and we all get smarter and know more and strive towards bettering our condition, curing our ills and minimizing suffering and maximizing happiness for all.

At least in my opinion it’s why scientific research while a truly neutral morally activity and generally done as an end unto itself - from a broadly humanist standpoint - is worth pursuing, even when the immediate benefits aren’t seen by the shortsighted.

sqgl@sh.itjust.works on 14 Jun 06:19 collapse

Even if we were the only country researching…

I have heard GOP politicians saying something like “why should we fund a cure for a disease and everyone else benefits without spending a cent?”

Why doesn’t their national pride on the world stage extend beyond sport?

Randomgal@lemmy.ca on 14 Jun 10:03 collapse

Because that wouldn’t make as much money.

sqgl@sh.itjust.works on 14 Jun 11:04 collapse

Olympic gold medals don’t make money. It is for national pride. Even hosting the games does not always make money.

Actually I am Aussie. 12 years ago it was calculated that each gold medal costs us AU$12m (so about US$11m in today’s money). It embarrasses me.

smh.com.au/…/they-kill-us-for-their-sport-william…

sqgl@sh.itjust.works on 14 Jun 11:21 collapse

I am no fan of Eurovision but it is good value for national pride:

Eurovision is funded by participating broadcasters and this contribution is a total of €6.2 million (£5.2 million), combined.

dailystar.co.uk/…/who-funds-eurovision-song-conte…

Jrockwar@feddit.uk on 14 Jun 11:37 collapse

Only 6M €? For an event of that size that feels a lot cheaper than I would have thought.

sqgl@sh.itjust.works on 14 Jun 12:39 collapse

Don’t forget that there is also income from advertising and ticket sales.

jsomae@lemmy.ml on 14 Jun 05:59 collapse

Trump also got the covid vaccine invented, produced, and distributed. It was probably the greatest thing he ever did but now he doesn’t even want to be associated with it. Alas. His lunacy knows no bounds.

atomicbocks@sh.itjust.works on 14 Jun 07:21 collapse

Yes and no, warp speed only needed to exist in the form it did because Trump had fired the existing pandemic response team.

jsomae@lemmy.ml on 14 Jun 16:06 collapse

Good point. On the other hand, Canada didn’t fare any better even without firing its pandemic response team. I suspect project warp speed would have been welcomed either way, even if it was more important in this timeline.

atomicbocks@sh.itjust.works on 14 Jun 16:27 collapse

“Canada’s per capita case rate has generally been less than half that of the US"

jsomae@lemmy.ml on 16 Jun 03:07 collapse

A million americans died of COVID (yes, some of them would have died without); but half a million would still be very bad.

52fighters@lemmy.sdf.org on 14 Jun 10:42 next collapse

Can someone clarify which blood test was used? I want to get tested every two years.

nutsack@lemmy.dbzer0.com on 14 Jun 11:45 collapse

just go to an oncologist and get screened

source: i did cancer

Harbinger01173430@lemmy.world on 14 Jun 12:54 next collapse

Yes but, is it profitable?

Someone has to ask the real world questions

Gsus4@mander.xyz on 14 Jun 12:59 collapse

If everyone gets tested yearly until they die, this could total as much as most cancer treatments and suffering combined and it would probably still be better for everyone if nobody has to go through that anymore.

HollowNaught@lemmy.world on 16 Jun 11:47 collapse

Bit misleading. Tumour-associated antigens can very easily be detected very early. Problem is, these are only associated with cancer, and provide a very high rate of false positives

They’re better used as a stepping stone for further testing, or just seeing how advanced a cancer is

That is to say, I’m assuming that’s what this is about, as i didnt rwad the article. It’s the first thing I thought of when I heard “cancer in bloodstream”, as the other options tend to be a bit more bleak

Edit: they’re talking about cancer “shedding genetic material”, which I hate how general they’re being. Probably talking about proto oncogenes from dead tumour debris, but seems different to what I was expecting