Scientists hail new antibiotic that can kill drug-resistant bacteria (www.theguardian.com)
from L4s@lemmy.world to technology@lemmy.world on 05 Jan 2024 12:00
https://lemmy.world/post/10344573

Scientists hail new antibiotic that can kill drug-resistant bacteria::Zosurabalpin has defeated strains of pneumonia and sepsis in mice, raising hopes for human trials

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autotldr@lemmings.world on 05 Jan 2024 12:00 next collapse

This is the best summary I could come up with:


Scientists have discovered an entirely new class of antibiotic that appears to kill one of three bacteria considered to pose the greatest threat to human health because of their extensive drug-resistance.

Zosurabalpin defeated highly drug-resistant strains of Carbapenem-resistant Acinetobacter baumannii (Crab) in mouse models of pneumonia and sepsis, and was being tested in human trials.

“Crab is a significant cause of infection in hospitals, particularly in people who are on ventilators,” said Dr Andrew Edwards, a senior lecturer in molecular microbiology at Imperial College London, who was not involved in the research.

Through a series of experiments published in Nature, Prof Daniel Kahne at Harvard University in Cambridge, US, and colleagues showed that the drug prevented LPS from being transported to the outer membrane of the bacterium, killing it.

While he stressed that this molecule alone would not solve the public health threat of antimicrobial resistant infections, the discovery could lay the foundations for future efforts to drug the same transport system in other bacteria.

It recommended that the government should consider establishing a small facility at the mothballed Rosalind Franklin laboratory in the West Midlands, which was originally set up to process Covid tests during the pandemic.


The original article contains 624 words, the summary contains 198 words. Saved 68%. I’m a bot and I’m open source!

[deleted] on 05 Jan 2024 13:38 next collapse

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AlpacaChariot@lemmy.world on 05 Jan 2024 18:36 next collapse

Antibiotics aren’t used against viruses (like the ones that cause a cold)

whenigrowup356@lemmy.world on 05 Jan 2024 23:26 next collapse

In some countries, they are

AlpacaChariot@lemmy.world on 05 Jan 2024 23:30 collapse

You know what I mean. They shouldn’t be, because they don’t do anything against viruses.

[deleted] on 05 Jan 2024 23:54 collapse

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wahming@monyet.cc on 06 Jan 2024 02:05 collapse

Not specific to China, can attest it’s pretty widespread throughout Asia to give antibiotics as a placebo.

BustinJiber@lemmy.world on 05 Jan 2024 14:05 next collapse

Bacteria: Hold my beer.

obinice@lemmy.world on 05 Jan 2024 17:29 collapse

That’s yeast

uriel238@lemmy.blahaj.zone on 05 Jan 2024 20:26 next collapse

We have way too many cases of XDRTB, often in impoverished, unindustrialized regions, so this is one of the outbreaks that needs some new treatments and a whole lot less corporate greed.

At the moment, we can build custom bacteriaphages, but currently, solutions like this are largely concerned with the movement of small green pieces of paper (which is odd because on the whole it isn’t the small green pieces of paper that are sick.)

HeyThisIsntTheYMCA@lemmy.world on 05 Jan 2024 21:24 next collapse

Ooo something new to be allergic to

runeko@programming.dev on 06 Jan 2024 00:05 collapse

. . . for now.